In this paper we analyze some of the major difficulties of informed consent. We consider insufficient to base IC on the principle of autonomy. We must not forget that the patient may be in a situation of extreme vulnerability and the good doctor should assume a degree of commitment and responsibility with his/her decisions. Our aim is to introduce the ethics of responsibility of Levinas in practice and theory of IC in order to generate a beneficent medical practice in which (...) the supervision and overseeing of the patient do not undermine his/her autonomy. (shrink)

International research enrolling human subjects has raised an ethical concern regarding the just distribution of benefits between the countries that design the research and the host communities. Although several universal declarations have expressed this concern, a gap between theory and practice continues to exist, as well as a significant divergence between the design of the research protocol and the social context where it will be implemented. Although institutional review boards have made a valuable effort to evaluate international research, their sensitivity (...) to the just sharing of research benefits as well as their attention to the social context must be evaluated. This article analyzes the distribution of benefits in a review of international research in Mexico and produces an ethical reflection based on the results. (shrink)

We start from an understanding of the human person as a communicative and symbolic reality. We emphasise the more subjective aspect of education, as showing the best of the person (educere) by creatively appropriating the treasures of history (educare). With these premises, we approach narratives that are surprising for the heterodoxy (resistance) they manifest, with respect to the social reality in which they were written, in the 1st century, in which they were written. In this approach it becomes evident that (...) the interruption of the silence of women, which appears in these narratives, shows the radical value of the human personal reality, opening an egalitarian educational space. (shrink)

En los relatos de María, la madre de Jesús, encontramos un modelo de la realidad personal humana en el dinamismo de su realización como un continuo estar-dando-de-sí que muestra su desbordamiento como realidad educanda, realidad abierta. En otros relatos se muestra a mujeres como testigos del encuentro con Jesús después de su muerte, un testimonio que es recibido por el grupo de Jesús y corroborado por los varones de la comunidad para hacerlo llegar más allá de sus fronteras. En el (...) testimonio recibido y la acción compartida se muestran los cimientos de una sociedad que se construye en igualdad. (shrink)

The objective of this research is to develop accurate forecasting models for chlorophyll-α concentrations at various depths in El Mar Menor, Spain. Chlorophyll-α plays a crucial role in assessing eutrophication in this vulnerable ecosystem. To achieve this objective, various deep learning forecasting techniques, including long short-term memory, bidirectional long short-term memory and gated recurrent uni networks, were utilized. The models were designed to forecast the chlorophyll-α levels with a 2-week prediction horizon. To enhance the models’ accuracy, a sliding window method (...) combined with a blocked cross-validation procedure for time series was also applied to these techniques. Two input strategies were also tested in this approach: using only chlorophyll-α time series and incorporating exogenous variables. The proposed approach significantly improved the accuracy of the predictive models, no matter the forecasting technique employed. Results were remarkable, with |$\overline{\sigma}$| values reaching approximately 0.90 for the 0.5-m depth level and 0.80 for deeper levels. The proposed forecasting models and methodologies have great potential for predicting eutrophication episodes and acting as decision-making tools for environmental agencies. Accurate prediction of eutrophication episodes through these models could allow for proactive measures to be implemented, resulting in improved environmental management and the preservation of the ecosystem. (shrink)

Corporate, Social, Ethical and Environmental Reporting should ideally discharge the accountability of an organisation to its stakeholders. Voluntary reporting has been characterised by a dearth of neutral and objective information such that the advocates of SEER recommend that it be made compulsory. Their underlying rationale is that legally specified disclosure requirements and enforcement mechanisms will enhance the quality of such reporting. This paper sets out to explore how realistic this scenario actually is, in view of the conflicting interpretations in the (...) literature on this subject. To that end, a survey of the reporting patterns of 78 of the largest Spanish companies between 2001 and 2003 examines the extent of their compliance with the ICAC-2002 standard, which obliged them to make environmental disclosures in their financial statements. The results suggest that progressive and improved regulation could increase the volume and quality of SEER disclosures. They also suggest, however, that persistent non-compliance means that the problems associated with voluntary disclosure still exist. Finally, through an impression management perspective, the study reveals, the diverse strategies, ranging from dismissal to concealment, that are employed by companies to avoid transparency. As regulation improves and enforcement expectations rise, it becomes more difficult to dismiss compulsory reporting norms. As a result, some firms engage in more complex concealment strategies to attain corporate legitimacy, depriving stakeholders of regulatory information. The latter point serves to reconcile apparently contradictory explanations in the literature as to whether legitimacy theory might explain partial compliance with SEER regulation. (shrink)

ABSTRACT International research enrolling human subjects has raised an ethical concern regarding the just distribution of benefits between the countries that design the research and the host communities. Although several universal declarations have expressed this concern, a gap between theory and practice continues to exist, as well as a significant divergence between the design of the research protocol and the social context where it will be implemented. Although institutional review boards have made a valuable effort to evaluate international research, their (...) sensitivity to the just sharing of research benefits as well as their attention to the social context must be evaluated. This article analyzes the distribution of benefits in a review of international research in Mexico and produces an ethical reflection based on the results. (shrink)

La gamificación o ludificación, entendida como la aplicación de la filosofía del juego en contextos no lúdicos, está experimentando en los últimos años un desarrollo espectacular en áreas de diversa naturaleza. Si bien está más que comúnmente aceptado que las funciones principales de los museos consisten en preservar y dar a conocer sus colecciones, resulta fundamental que logren conectar de manera satisfactoria con los usuarios empleando para ello medios y estrategias innovadoras y accesibles. En las siguientes páginas ponemos de manifiesto (...) cómo la gamificación no es sino un recurso idóneo para motivar, fidelizar e influir en el comportamiento de los usuarios. (shrink)

Corporate, Social, Ethical and Environmental Reporting should ideally discharge the accountability of an organisation to its stakeholders. Voluntary reporting has been characterised by a dearth of neutral and objective information such that the advocates of SEER recommend that it be made compulsory. Their underlying rationale is that legally specified disclosure requirements and enforcement mechanisms will enhance the quality of such reporting. This paper sets out to explore how realistic this scenario actually is, in view of the conflicting interpretations in the (...) literature on this subject. To that end, a survey of the reporting patterns of 78 of the largest Spanish companies between 2001 and 2003 examines the extent of their compliance with the ICAC-2002 standard, which obliged them to make environmental disclosures in their financial statements. The results suggest that progressive and improved regulation could increase the volume and quality of SEER disclosures. They also suggest, however, that persistent non-compliance means that the problems associated with voluntary disclosure still exist. Finally, through an impression management perspective, the study reveals, the diverse strategies, ranging from dismissal to concealment, that are employed by companies to avoid transparency. As regulation improves and enforcement expectations rise, it becomes more difficult to dismiss compulsory reporting norms. As a result, some firms engage in more complex concealment strategies to attain corporate legitimacy, depriving stakeholders of regulatory information. The latter point serves to reconcile apparently contradictory explanations in the literature as to whether legitimacy theory might explain partial compliance with SEER regulation. (shrink)

Para probar que existe verdaderamente una literatura hispanoamericana que posee caracteres de fines de siglo, se cotejan entre sí dos, tres, cuatro textos pertenecientes a géneros diferentes y animados por proyectos ideológicos y estéticos opuestos y se demuestra, en general con poco rigor que, paradójicamente, están regidos por los mismos principios de construcción. Resultaría verificada, de tal modo la existencia en la América hispana, de una literatura específicamente finisecular. Mi deseo, hoy, es reflexionar con ustedes a contramano de esa corriente. (...) Pretendo, en consecuencia, averiguar disimilitudes, en el ánimo de recordar que lo propio del discurso literario, tanto a finales como a mediados o a principios de cualquier siglo, es la diversidad, la oposición, el antagonismo. (shrink)

Luis Jiménez Moreno murió en octubre de 2007 a los 77 años de edad. Durante los últimos 30 años perteneció a la Universidad Complutense, de la que llegó a ser catedrático. Había estudiado en Salamanca, Roma, Valencia y Munich. Su tesis doctoral sobre el pensamiento antropológico de Nietzsche fue dirigida por Aranguren. Fue catedrático de instituto en Andújar, Ávila y Badalona, y profesor de universidad en Barcelona y Madrid. El presente artículo recoge los datos fundamentales de su vida, así (...) como toda su obra dividida en libros, artículos, ensayos, conferencias, ponencias y comunicaciones en congresos, seminarios, simposios, reuniones científicas, etc. (shrink)

Se revisan las noticias que la prensa nacional publicó durante la inauguración del Museo Nacional de Antropología en 1964, y se exploran otras noticias de naturaleza semejante, como la inauguración del Museo Nacional del Virreinato de Tepotzotlán y el Museo de Arte Moderno, al tiempo que se reflexiona sobre la identidad nacional, el patrimonio y el papel del museo en la sociedad y la cultura mexicana.

Histamine is a multifunctional biogenic amine with relevant roles in intercellular communication, inflammatory processes and highly prevalent pathologies. Histamine biosynthesis depends on a single decarboxylation step, carried out by a PLP-dependent histidine decarboxylase activity (EC 4.1.1.22), an enzyme that still remains to be fully characterized. Nevertheless, during the last few years, important advances have been made in this field, including the generation and validation of the first three-dimensional model of the enzyme, which allows us to revisit previous results and conclusions. (...) This essay provides a comprehensive review of the current knowledge of the structural and functional characteristics of mammalian histidine decarboxylase. BioEssays 27:57–63, 2005. © 2004 Wiley Periodicals, Inc. (shrink)

La relación de discrepancia y coincidencia de las causas de muerte entre el diagnóstico clínico y anatomopatológico constituye de forma indirecta un indicador de calidad de la atención médica. Son múltiples los ejemplos de enfermedades descubiertas o esclarecidas gracias a la autopsia, que tiene en la correlación clinicopatológica un basamento fundamental. Se estableció como objetivo de investigación describir los principales vínculos históricos entre las especialidades de medicina interna y anatomía patológica, que tienen como enlace esencial la correlación clínico patológica, atendiendo (...) a que no puede existir contradicción antagónica entre enfermo y enfermedad; la medicina interna y la anatomía patológica no pueden verse aisladas ni separadas. The difference and similarity relationship of death causes between the clinical and anatomy-pathological diagnosis is, indirectly, a medical care quality indicator. Thanks to autopsy, which has the clinical-pathological correlation as a main basis, numerous diseases have been discovered or clarified. Discovering the main historical relations between Internal Medicine and Pathological Anatomy specialties was established as the objective of the research. These specialties have the clinical-pathological correlation as a main link, taking into account that there cannot be a conflicting contradiction between the sick and the disease; Internal Medicine and Pathological Anatomy cannot be seen in an isolated or separate way. (shrink)

The essential role of creativity has been highlighted in several human knowledge areas. Regarding the neural underpinnings of creativity, there is evidence about the role of left dorsolateral prefrontal cortex (DLPFC) and left inferior frontal gyrus (IFG) on divergent thinking (DT) and convergent thinking (CT). Transcranial stimulation studies suggest that the left DLPFC is associated with both DT and CT, whereas left IFG is more related to DT. However, none of the previous studies have targeted both hubs simultaneously and compared (...) transcranial direct current stimulation (tDCS) and random noise stimulation (tRNS). Additionally, given the relationship between cognitive flexibility and creativity, we included it in order to check if the improvement in creativity may be mediated by cognitive flexibility. In this double-blind, between-subjects study, 66 healthy participants were randomly assigned to one of three groups (N = 22) that received a transcranial direct current stimulation (tDCS), transcranial random noise stimulation (tRNS), or sham for 20 min. The tDCS group received 1.5 mA with the anode over the left DLPFC and cathode over the left IFG. Locations in tRNS group were the same and they received 1.5 mA of high frequency tRNS (100–500 Hz). Divergent thinking was assessed before (baseline) and during stimulation with unusual uses (UU) and picture completion (PC) subtests from Torrance Creative thinking Test, whereas convergent thinking was evaluated with the remote association test (RAT). Stroop test was included to assess cognitive flexibility. ANCOVA results of performance under stimulation (controlling for baseline performance) showed that there were significant differences in PC (F = 3.35, p = 0.042, np2 = 0.10) but not in UU (F = 0.61, p = 0.546) and RAT (F = 2.65, p = 0.079) scores. Post-hoc analyses showed that tRNS group had significantly higher scores compared to sham (p = 0.004) in PC. More specifically, tRNS showed higher performance in fluency (p = 0.012) and originality (p = 0.021) dimensions of PC compared to sham. Regarding cognitive flexibility, we did not find any significant effect of any of the stimulation groups (F = 0.34, p = 0.711). Therefore, no further mediation analyses were performed. Finally, the group that received tDCS reported more adverse effects than sham group (F = 3.46, p = 0.035). Altogether, these results suggest that tRNS may have some advantages over tDCS in DT. (shrink)

El conocimiento histórico –entendido como un proceso metacognitivo de asimilación constructiva sobre el pasado para explicar fenómenos– comporta un análisis del impacto y la transcendencia de determinados acontecimientos y procesos históricos, en cuya comprensión y valoración influye el concepto de relevancia histórica. Desde esta perspectiva es necesario implementar propuestas de evaluación sólidas, vinculadas al desarrollo competencial. El objetivo de este estudio es diseñar una guía de caracterización de los instrumentos evaluativos –actividades y ejercicios– más utilizados por el profesorado de Historia, (...) con el fin de optimizar los procesos de evaluación de esta competencia mediante una serie de descriptores estructurales, competenciales y transferenciales. Estos indicadores de pertinencia pueden marcar el camino de aquellos docentes que deseen perfeccionar su manera de evaluar lo históricamente determinante. En conclusión, este innovador planteamiento supone un proceso de formación continua del profesorado que contribuye a la mejora de la calidad educativa. (shrink)

El objetivo de este trabajo es analizar las temáticas sobre las que se vieneenseñando e investigando en el marco de la Filosofía del Derecho, con el finde anticipar la hoja de ruta sobre la que se van a desempeñar aquellos quese dedican a las diversas temáticas que se enmarcan en nuestra disciplina.Se observará que la Filosofía del Derecho ha sido capaz de adaptarse alcorrer cambiante de los tiempos, ofreciendo reflexiones y aparato críticosólido y riguroso con el que afrontar nuevos problemas (...) en escenarios convulsos.El reto será trasladar a las aulas ese bagaje intelectual y reubicarseen los planes de estudio. (shrink)

Since the 1980s, there has been a significant increase in the number of studies concerning Andalusian rural settlements linked to irrigated agriculture, both related to large suburban green belts and to small hydraulic systems. In the vast areas where water is scarce, the settlement apparently would have been concentrated in cities and fortified towns, leaving without population most of the dry lands between them. However, thanks to the intensive survey of one of these regions, La Mancha’s Southeastern area, we are (...) recording a dense rural settlement corresponding to a pattern unknown until now. It consists basically of small villages in plain, devoid of community defense elements, which must have been inhabited by humble peasants, judging by the modesty of the architecture and domestic goods. Surely they make use of the scanty natural resources, which have traditionally oriented the economy of the region towards livestock and rainfed agriculture. In particular, the studied settlement would be related to the demand of wool for the export oriented textile production of the region, within the framework of the commercial expansion of that period. Apparently, most of those villages could have appeared in the eleventh century, disappearing in the middle of the thirteenth century because of the Christian conquest. Their existence would be associated with a general context of population growth that pushed the competition between urban elites and peasants pursuing the privileged agricultural areas, as well as the colonization of less favorable production areas. (shrink)

Existe uma aparente contradição entre a negação kantiana do direito de resistência expressa na filosofia do direito e a sua apologia à Revolução Francesa abordada na história filosófica. No entanto, esta contradição se dissolve tão logo se compreende que Kant considerou que a Revolução Francesa não constitui precisamente uma revolução, uma vez que isto implicaria que o povo retornasse ao estado de natureza com relação ao soberano deposto, mas uma reforma constitucional empreendida involuntariamente pelo próprio rei Luis XVI que transferiu (...) a soberania aos representantes do povo ao convocar os Estados Gerais, os quais não tinham a obrigação de restituí-la ao soberano anterior, em lugar disso, preferiram se declarar em Assembleia Nacional e elaborar a constituição republicana, a única conforme a vontade unificada do povo. (shrink)

Luis Jiménez abordó los problemas filosóficos fundamentalmente desde un punto de vista antropológico, teniendo siempre en cuenta la aportación de las ciencias positivas. Centrado en los autores contemporáneos, abrió tres espacios de reflexión: 1º, el humanismo práctico del pensamiento español, desde el Barroco hasta Unamuno, Ortega, d’Ors y Zubiri. 2º, el vitalismo antropológico-axiológico de Nietzsche. 3º, la libertad, la dignidad y la igualdad de los hombres en la Ilustración a partir de Rousseau y de Kant.Luis Jiménez wrote about (...) Philosophical problems bassicaly from an anthropo- logical viewpoint. He always hold in higth esteem Science’s contributions. He focused on Contemporary authors and he opened three thinking places: 1. Practical Humanism of Spanish Thougth: from Baroque age to Unamuno, Ortega, D’Ors and Zubiri. 2. Nietzsche’s Anthropological and Axiological life. 3. Freedom, Dignity and Equality from Rousseau to Kant. (shrink)

Background: Heart rate variability (HRV) has been considered as a measure of heart-brain interaction and autonomic modulation, and it is modified by cognitive and attentional tasks. In cognitive tasks, HRV was reduced in participants who achieved worse results. This could indicate the possibility of HRV predicting cognitive performance, but this association is still unclear in a high cognitive load sport such as chess Objective: To analyse modifications on HRV and subjective perception of stress, difficulty and complexity in different chess problem (...) tasks. Design: HRV was assessed at baseline. During the chess problems, HRV was also monitored, and immediately after chess problems the subjective stress, difficulty and complexity were also registered. Method: A total of 16 male chess players, age: 35.19 (13.44) and ELO: 1927.69 (167.78) were analysed while six chess problem solving tasks with different level of difficulty were conducted (two low level, two medium level and two high level chess problems). Participants were classified according to their results into two groups: high performance or low performance. Results: Friedman test showed a significant effect of tasks in HRV indexes and perceived difficulty, stress and complexity in both high and low performance groups. A decrease in HRV was observed in both groups when chess problems difficulty increased. In addition, HRV was significantly higher in the high performance group than in the low performance group during chess problems. Conclusions: An increase in autonomic modulation was observed to meet the cognitive demands of the problems, being higher while the difficulty of the tasks increased. Non-linear HRV indexes seem to be more reactive to tasks difficulty, being an interesting and useful tool in chess training. (shrink)

BackgroundA combination of theoretical and practical approaches is required to learn and acquire ethical competencies in caring. Occasionally, reflection on practical action differs from theoretica...

Given the potential that environmentally oriented anti-consumption (EOA) has in achieving environmental sustainability, the authors draw upon marketing, management, environmental, and psychology studies to conceptualize and delimit EOA, differentiating it from other (related but distinct) phenomena. In addition, the authors review the available literature at the individual (micro) level and summarize research on the antecedents and meanings of broad and specific/strict EOA practices with different targets. Furthermore, the authors propose an agenda for future research, which reflects on EOA not only (...) at the individual (micro) level, but also lays out new opportunities for EOA work at organizational (meso), industry, and national (macro) levels. The work presented here hopes to spark multilevel research on EOA, its antecedents and consequences, and reactions to EOA phenomena. (shrink)

El trabajo propone una reflexión en torno al hecho histórico como determinante de la vida presente y, por lo tanto, del destino de los hombres, los pueblos y civilizaciones. A la luz de lo planteado por Nietzsche en la Segunda consideración intempestiva, la historia puede ser narrada de forma monumental, anticuaria o crítica. Estas formas constituyen modos de vivir el presente y el destino propio. Se busca entender cada una de estas posibles actitudes frente al pasado, a la vez que (...) se indaga el sentido de dicha interpretación para el hombre de hoy, inmerso en su singular experiencia de la temporalidad. (shrink)